RAF Typhoon FGR4s have operated alongside French aircraft in a coordinated attack targeting an hidden munitions depot in Syrian territory operated by the Daesh militant organization, per a report from the UK Ministry of Defence.
The facility, identified by surveillance, was believed to be containing munitions and bombs, the release indicated, and was located in mountainous terrain just above the historic site of Palmyra in the heart of Syria.
"Our aircraft employed Paveway IV guided bombs to target a several entry passages leading to the site... preliminary assessments are that the target was engaged successfully," the ministry announced.
There was no indication of any civilian impact in the operation late on Saturday and every plane involved made a safe return, the ministry further stated.
The Typhoon fighters were assisted by a Voyager aerial refuelling aircraft.
Daesh - alternatively referred to as ISIS - established jihadist rule over significant areas in both Syria and Iraq until 2019.
"This strike underscores our UK leadership, and commitment to operate in unison with our partners, to eliminate any revival of Daesh and their dangerous and violent ideologies in the region," Britain's Defence Chief John Healey said.
British military aircraft have performed overwatch operations over Syrian airspace to "deter any efforts to regroup" of Islamic State following its defeat at the Baghuz confrontation in 2019, the ministry said.
"I must thank all the members of our armed forces who took part in this mission for their skill and their valour," Healey said. "They were among numerous UK service members on duty over the holidays. This mission, to take out militants who threaten our way of life, demonstrates how British military are ready to step up, continuously, protecting the UK domestically and powerful internationally."
In December, the American forces executed what it called a "major assault" on Daesh sites in the country, subsequent to an assault resulted in the deaths of two US troops and a local interpreter in the Palmyra area.
The United Nations says IS still maintains an estimated 5,000 to 7,000 militants in both countries.